Metastatic Thyroid Carcinoma Arising from Congenital Goiter due to Mutation in the Thyroperoxidase Gene1
نویسندگان
چکیده
منابع مشابه
Thyroid carcinoma in multinodular goiter
Background: It is suggested that hyperthyroidism protects against thyroid malignancy. It was suggested that the incidence of malignancy is lower in toxic multinodular goiters than in non-toxic multinodular goiters. Recent studies show controversies. Material and methods: The aim of this study is to determine the incidence and type of thyroid carcinoma in toxic and nontoxic multinodular goiter i...
متن کاملA rare case of poorly differentiated thyroid carcinoma probably arising from a nodular goiter
BACKGROUND Some poorly differentiated thyroid carcinomas (PDTC) arise from pre-existing, well-differentiated carcinomas of follicular cell origin; however, others most likely arise de novo. The case of a PDTC adjacent to a pre-existing nodular goiter is very rare. CASE PRESENTATION A patient had a PDTC, a widely invasive, cellular tumor with cells that lacked the nuclear features of a papilla...
متن کاملPapillary Thyroid Carcinoma with Lung Metastasis Arising from Dyshormonogenetic Goiter: A Case Report
Prior radiation exposure is the best known risk factor for thyroid cancers, and papillary thyroid carcinoma (PTC) may arise from dyshormonogenetic goiter. A 17-year-old female patient was admitted to the department of chest diseases with respiratory symptoms. The patient had undergone a thyroid surgery for goiter at the age of 9. A bilateral nodular opacity was detected by radiological examinat...
متن کاملSquamous Cell Differentiation in Metastatic Papillary Thyroid Carcinoma: Metaplastic
Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1) and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...
متن کاملCongenital thyroid hemiagenesis with multinodular goiter
Thyroid hemiagenesis is a rare form of thyroid dysgenesis characterized by an absence of half of the thyroid gland. Developmental hemi-thyroid anomalies can result from either an abnormal descent or an agenesis of one lobe of the thyroid gland. We report a case of a 40-year-old woman with history of a longstanding gradually progressive thyroid swelling without any complication. An ultrasonograp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1998
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.83.11.5264